🚨 Big news: Curetopia & MIRA partner to accelerate rare disease cures @eperlste x @blader is the DeSci dream team we've been waiting for Here's how a new generation of biotech builders is bootstrapping the Internet of Science in the face of trad bio failing patients 🧵👇
Our story begins on Christmas Day last year, when @blader received a mysterious memecoin in his crypto wallet called "MIRA", named after his daughter who has a rare brain tumor with no known treatments. Moved by her story, anons had launched $MIRA to raise research funds. Despite volatility, $MIRA drove $1M+ to one of the few labs studying Mira's condition 🤯
Crypto opens up new channels of funding for emerging and overlooked areas of biomedicine: > Peer-to-peer networks where patients pool resources > No middlemen → Money flows directly to Researchers > Tokenized communities → holders allocate funding and can see upside Meanwhile, 2024 marked biotech's deepest bear market in 40 years 🥶
The data isn't pretty: ❌ New drug approvals have fallen 50% in the past decade ❌ R&D costs have skyrocketed → $2.3B per new drug ❌ NIH funding has barely budged in real dollars Eroom's Law hits different, leaving rare diseases like Mira’s completely behind.
Rare disease research is stuck in limbo: > 10,000+ rare diseases > 90% have no FDA-approved treatment > Patient communities don't reach Big Pharma's required TAM Enter @eperlste - Harvard PhD, @ycombinator alum & new breed of startup scientist with a chip on his shoulder 🏴‍☠️
DeSci flips the model: 🔹 Decentralized trials → Cut costs & move fast 🔹 Onchain research funding → No middlemen, no gatekeepers 🔹 Direct-to-patient drug development → No waiting for Big Pharma And Ethan is proving it works.
Siqi himself is a startup veteran: 🔹 Founder of Runway → finance platform backed by a16z 🔹 Scaled consumer apps to millions of users at Zynga 🔹 Brings startup execution to biotech Big Pharma is slow, Siqi is here to move fast - a mission-driven warrior like the millions of rare families.
Siqi & Ethan are going all-in on Curetopia Architect of the $1M Christmas Miracle + the biotech rebel who hacked drug development are doubling down: 🔹 Siqi joins Curetopia as a core contributor & advisor 🔹 Siqi pledges his $MIRA holdings (13.8% of supply) to Curetopia's DAO 🔹 MiraDAO gets 1% of Curetopia supply, vested over 4 years 🔹 Curetopia airdrops 1% of the $CURES token supply to MIRA holders, vested linearly over 2 years (snapshot taken Feb 24 2025) MIRA holders get direct skin in the game to fund and participate in rare disease research. From memecoin madness → medical movement.
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