🚨 Big news: Curetopia & MIRA partner to accelerate rare disease cures
@eperlste x @blader is the DeSci dream team we've been waiting for
Here's how a new generation of biotech builders is bootstrapping the Internet of Science in the face of trad bio failing patients 🧵👇
Our story begins on Christmas Day last year, when @blader received a mysterious memecoin in his crypto wallet called "MIRA", named after his daughter who has a rare brain tumor with no known treatments.
Moved by her story, anons had launched $MIRA to raise research funds.
Despite volatility, $MIRA drove $1M+ to one of the few labs studying Mira's condition 🤯
Crypto opens up new channels of funding for emerging and overlooked areas of biomedicine:
> Peer-to-peer networks where patients pool resources
> No middlemen → Money flows directly to Researchers
> Tokenized communities → holders allocate funding and can see upside
Meanwhile, 2024 marked biotech's deepest bear market in 40 years 🥶
The data isn't pretty:
❌ New drug approvals have fallen 50% in the past decade
❌ R&D costs have skyrocketed → $2.3B per new drug
❌ NIH funding has barely budged in real dollars
Eroom's Law hits different, leaving rare diseases like Mira’s completely behind.
Rare disease research is stuck in limbo:
> 10,000+ rare diseases
> 90% have no FDA-approved treatment
> Patient communities don't reach Big Pharma's required TAM
Enter @eperlste - Harvard PhD, @ycombinator alum & new breed of startup scientist with a chip on his shoulder 🏴☠️
DeSci flips the model:
🔹 Decentralized trials → Cut costs & move fast
🔹 Onchain research funding → No middlemen, no gatekeepers
🔹 Direct-to-patient drug development → No waiting for Big Pharma
And Ethan is proving it works.
Siqi himself is a startup veteran:
🔹 Founder of Runway → finance platform backed by a16z
🔹 Scaled consumer apps to millions of users at Zynga
🔹 Brings startup execution to biotech
Big Pharma is slow, Siqi is here to move fast - a mission-driven warrior like the millions of rare families.
Siqi & Ethan are going all-in on Curetopia
Architect of the $1M Christmas Miracle + the biotech rebel who hacked drug development are doubling down:
🔹 Siqi joins Curetopia as a core contributor & advisor
🔹 Siqi pledges his $MIRA holdings (13.8% of supply) to Curetopia's DAO
🔹 MiraDAO gets 1% of Curetopia supply, vested over 4 years
🔹 Curetopia airdrops 1% of the $CURES token supply to MIRA holders, vested linearly over 2 years (snapshot taken Feb 24 2025)
MIRA holders get direct skin in the game to fund and participate in rare disease research.
From memecoin madness → medical movement.
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